List II:
Substances under evaluation for endocrine disruption under an EU legislation
This list contains substances that are currently under evaluation in an EU legislative process due to explicit concerns for possible endocrine disrupting properties. This could be due to a Member State or ECHA having included the compound on the CoRAP list (REACH), or due to an ongoing evaluation of endocrine disrupting properties under the Cosmetics Products Regulation. Pesticides and biocides which are concluded as endocrine disruptors in the scientific committees are placed on List II until legally adopted, at which time they are transferred to List I.
Latest update 2023/11
Name and abbreviation Sortér faldende | CAS no. | EC / List no. | Health Effects | Environmental Effects | Status | Regulatory Field |
---|---|---|---|---|---|---|
1-(5,6,7,8-tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthyl)ethan-1-one | 21145-77-7, 1506-02-1 | 244-240-6, 216-133-4 | Yes |
CoRAP list year: 2020 |
REACH | |
1,1'-[ethane-1,2-diylbisoxy]bis[2,4,6-tribromobenzene] | 37853-59-1 | 253-692-3 | Yes | REACH | ||
1,3-dihydro-4(or 5)-methyl-2H-benzimidazole-2-thione | 53988-10-6 | 258-904-8 | Yes |
CoRAP list year: 2018 |
REACH | |
1,3-dihydro-4(or 5)-methyl-2H-benzimidazole-2-thione, zinc salt | 61617-00-3 | 262-872-0 | Yes |
CoRAP list year: 2018 |
REACH | |
1,3,4,6,7,8- hexahydro-4,6,6,7,8,8- hexamethylindeno[5 ,6-c]pyran (HHCB) | 1222-05-5 | 214-946-9 | Yes | Yes |
CoRAP list year: 2022 |
REACH |
2-[4-[2-[4-(2-hydroxyethoxy)phenyl]propan-2-yl]phenoxy]ethanol | 32492-61-8 | 500-082-2 | Yes |
CoRAP list year: 2025 |
REACH | |
2-Ethylhexyl trans-4-methoxycinnamate (OMC) | 5466-77-3, 83834-59-7 | 226-775-7, 629-661-9 | Yes | Yes |
CoRAP list year: 2016 Commission EDC list year*: 2019 |
REACH, Cosmetics |
2-Propenoic acid, methyl ester, reaction products with mixed O,O-bis(branched and linear pentyl and iso-Bu) phosphorodithioates | 93925-38-3 | 300-340-2 | Yes | Yes |
CoRAP list year: 2023 |
REACH |
2-tert-butyl-4-methoxyphenol | 25013-16-5 | 246-563-8 | Yes |
Commission EDC list year*: 2019 |
Cosmetics | |
2,2-dibromo-2-cyanoacetamide (DBNPA) | 10222-01-2 | 233-539-7 | Yes | Yes | Biocides | |
2,2,6,6-tetrabromo-4,4-isopropylidenediphenol | 79-94-7 | 201-236-9 | Yes | Yes |
CoRAP list year: 2015 |
REACH |
2,2′,6,6′-Tetra-tert-butyl-4,4′- methylenediphenol | 118-82-1 | 204-279-1 | Yes |
CoRAP list year: 2014 |
REACH | |
2,4-di-tert-butylphenol | 96-76-4 | 202-532-0 | Yes | Yes |
CoRAP list year: 2017 |
REACH |
2,6-di-tert-butyl-p-cresol; butylated hydroxytoluene (BHT) | 128-37-0 | 204-881-4 | Yes |
CoRAP list year: 2016 Commission EDC list year*: 2019 |
REACH | |
3-methylpyrazole | 1453-58-3 | 215-925-7 | Yes |
CoRAP list year: 2018 |
REACH | |
3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl acrylate | 17527-29-6 | 241-527-8 | Yes |
CoRAP list year: 2016 |
REACH | |
3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl methacrylate | 2144-53-8 | 218-407-9 | Yes |
CoRAP list year: 2016 |
REACH | |
4-(4-isopropoxyphenylsulfonyl)phenol (D-8) | 95235-30-6 | 405-520-5 | Yes |
CoRAP list year: 2025 |
REACH | |
4-tert-butylphenol | 98-54-4 | 202-679-0 | Yes |
Environmental candidate list year: 2019 CoRAP list year: 2014 |
REACH | |
4,4'-isopropylidenedi-o-cresol | 79-97-0 | 201-240-0 | Yes | Yes |
CoRAP list year: 2021 |
REACH |
6,6'-di-tert-butyl-4,4'-butylidenedi-m-cresol | 85-60-9 | 201-618-5 | Yes |
CoRAP list year: 2019 |
REACH | |
6,6'-di-tert-butyl-4,4'-thiodi-m-cresol | 96-69-5 | 202-525-2 | Yes |
CoRAP list year: 2015 |
REACH | |
Asulam | 3337-71-1 | 222-077-1 | Yes | Pesticides | ||
Benthiavalicarb | 413615-35-7 | 609-913-4 | Yes | Pesticides | ||
Benzophenone-1 (BP-1) | 131-56-6 | 205-029-4 | Yes |
Commission EDC list year*: 2019 |
REACH, Cosmetics | |
Benzophenone-2 | 131-55-5 | 205-028-9 | Yes |
Commission EDC list year*: 2019 |
Cosmetics | |
Benzophenone-4 (BP-4) | 4065-45-6 | Yes |
Commission EDC list year*: 2019 |
REACH, Cosmetics | ||
Benzophenone-5 (BP-5) | 6628-37-1 | 613-918-7 | Yes |
Commission EDC list year*: 2019 |
Cosmetics | |
Benzotriazole | 95-14-7 | 202-394-1 | Yes |
CoRAP list year: 2016 |
REACH | |
Benzyl salicylate | 118-58-1 | 204-262-9 | Yes | Yes |
Commission EDC list year*: 2019 |
REACH, Cosmetics |
Bis(2-propylheptyl) phthalate | 53306-54-0 | 258-469-4 | Yes |
CoRAP list year: 2020 |
REACH | |
Bis(dibutyldithiocarbamato-S,S')copper | 13927-71-4 | 237-695-7 | Yes | Yes |
CoRAP list year: 2020 |
REACH |
Butanoic acid, 4-amino-4-oxosulfo-, N-coco alkyl derivs., monosodium salts, compds. with triethanolamine | 98171-53-0 | 308-662-5 | Yes | Yes |
CoRAP list year: 2023 |
REACH |
Butanone | 78-93-3 | 201-159-0 | Yes |
CoRAP list year: 2018 |
REACH | |
Butyl 4-hydroxybenzoate; Butylparaben | 94-26-8 | 202-318-7 | Yes | Health candidate list year: 2020 Commission EDC list year*: 2019 |
REACH, Cosmetics | |
Butylphenyl methylpropianol | 80-54-6 | 201-289-8 | Yes |
Commission EDC list year*: 2019 |
Cosmetics | |
Chlorobenzene | 108-90-7 | 203-628-5 | Yes |
CoRAP list year: 2023 |
REACH | |
Clofentezine | 74115-24-5 | 277-728-2 | Yes | Pesticides | ||
Cyanamide | 420-04-2 | 206-992-3 | Yes | Yes | Biocides | |
Cyclomethicone | 69430-24-6, 556-67-2, 541-02-6, 540-97-6 | 614-966-1, 209-136-7, 208-764-9, 208-762-8 | Yes |
Commission EDC list year*: 2019 |
Cosmetics | |
Daidzein | 486-66-8 | 207-635-4 | Yes |
Commission EDC list year*: 2019 |
Cosmetics | |
Decamethylcyclopentasiloxane (D5) | 541-02-6 | 208-764-9 | Yes |
Commission EDC list year*: 2019 |
Cosmetics | |
Deltamethrin | 52918-63-5 | 258-256-6 | Yes |
Commission EDC list year*: 2019 |
Biocides, Cosmetics | |
Dicyclohexyl phthalate (DCHP) | 84-61-7 | 201-545-9 | Yes | Health candidate list year: 2018 CoRAP list year: 2017 |
REACH | |
Dimethomorph | 110488-70-5 | 404-200-2 | Yes | Yes | Pesticides | |
dioctyltin oxide | 870-08-6 | 212-791-1 | Yes | Yes |
CoRAP list year: 2024 |
REACH |
Diuron | 330-54-1 | 206-354-4 | Yes | Yes |
CoRAP list year: 2014 |
REACH, Biocides |
EDDHMAFEK | 405-420-1 | Yes |
CoRAP list year: 2021 |
REACH | ||
Esterification products of 1,3-dioxo-2-benzofuran-5-carboxylic acid with nonan-1-ol | 941-303-6 | Yes | Yes |
CoRAP list year: 2025 |
REACH | |
Genistein | 446-72-0 | 207-174-9 | Yes |
Commission EDC list year*: 2019 |
Cosmetics | |
Isopentyl p-methoxycinnamate | 71617-10-2 | 275-702-5 | Yes |
CoRAP list year: 2016 |
REACH | |
Mepanipyrim | 110235-47-7 | 432-140-7 | Yes | Yes | Pesticides | |
Methylparaben | 99-76-3 | 202-785-7 | Yes |
CoRAP list year: 2014 Commission EDC list year*: 2019 |
REACH, Cosmetics | |
Metiram | 9006-42-2 | 618-430-8 | Yes | Pesticides | ||
Metribuzin | 21087-64-9 | 244-209-7 | Yes | Pesticides | ||
Oligomerisation and alkylation reaction products of 2-phenylpropene and phenol | 68512-30-1 | 270-966-8 | Yes |
CoRAP list year: 2012 |
REACH | |
Oxybenzone (BP-3) | 131-57-7 | 205-031-5 | Yes | Yes |
CoRAP list year: 2014 |
REACH |
Phenol, isopropylated, phosphate (3:1) | 68937-41-7 | 273-066-3 | Yes | Yes |
CoRAP list year: 2020 |
REACH |
phenol, styrenated,reaction mass of 2,4,6-tris(1-phenyl-ethyl)phenol and Bis(1-phenylethyl) phenol | 61788-44-1 | 262-975-0 | Yes |
CoRAP list year: 2014 |
REACH | |
Propiconazole | 60207-90-1 | 262-104-4 | Yes | Biocides | ||
Propyl 4-hydroxybenzoate; Propylparaben | 94-13-3 | 202-307-7 | Yes | Yes |
CoRAP list year: 2015 |
REACH, Cosmetics |
reaction mass of 1-(1,2,3,4,5,6,7,8-octahydro-2,3,8,8-tetramethyl-2-naphthyl)ethan-1-one and 1-(1,2,3,4,6,7,8,8a-octahydro-2,3,8,8-tetramethyl-2-naphthyl)ethan-1-one and 1-(1,2,3,5,6,7,8,8a-octahydro-2,3,8,8-tetramethyl-2-naphthyl)ethan-1-one | - | 915-730-3 | Yes | Yes |
CoRAP list year: 2017 |
REACH |
Reaction mass of p-t-butylphenyldiphenyl phosphate and bis(p-t-butylphenyl) phenyl phosphate | 939-505-4 | Yes | Yes |
CoRAP list year: 2023 |
REACH | |
Reaction products of phosphoryl trichloride and 2-methyloxirane | 1244733-77-4 | 807-935-0 | Yes |
CoRAP list year: 2022 |
REACH | |
Resorcinol | 108-46-3 | 203-585-2 | Yes |
CoRAP list year: 2019 |
REACH | |
Thiabendazole | 148-79-8 | 205-725-8 | Yes | Pesticides | ||
Triclosan | 3380-34-5 | 222-182-2 | Yes |
CoRAP list year: 2012 |
REACH, Cosmetics | |
Triflusulfuron-methyl | 126535-15-7 | 603-146-9 | Yes | Yes | Pesticides | |
Triphenyl phosphate (TPP) | 115-86-6 | 204-112-2 | Yes | Yes |
CoRAP list year: 2017 Commission EDC list year*: 2019 |
REACH, Cosmetics |
Tris[2-chloro-1-(chloromethyl)ethyl] phosphate | 13674-87-8 | 237-159-2 | Yes |
CoRAP list year: 2024 |
REACH | |
Ziram | 137-30-4 | 205-288-3 | Yes |
CoRAP list year: 2012 |
REACH |
*Commission EDCs cosmetics priority list year